Manchester United boss Ole Gunnar Solskjaer makes three changes to the team that started the 2-2 draw against Atalanta on Tuesday night.
Victor Lindelof has recovered and takes the place of the injured Raphael Varane, Fred comes in for the suspended Paul Pogba while in attack, Mason Greenwood comes in for Marcus Rashford.
United XI: De Gea, Wan-Bissaka, Shaw, Lindelof, Bailly, Maguire, Fred, McTominay, Fernandes, Greenwood, Ronaldo.
Subs: Henderson, Martial, Rashford, Lingard, Dalot, Sancho, Telles, Matic, Van De Beek.
City XI: Ederson, Walker, Dias, Stones, Cancelo, Rdori, Gundogan, Foden, De Bruyne, Silva, Jesus.
Subs: Steffen, Carson, Ake, Sterling, Grealish, Zinchenko, Fernandinho, Mahrez, Palmer.