Manchester United stars Luke Shaw and Casemiro need to be rested following Thursday’s 4-1 victory over Real Betis.
Manchester United responded to the humiliating 7-0 defeat to Liverpool with an impressive 4-1 win over Spanish side Betis in the first leg of the last-16 tie.
Manchester United boss Erik ten Hag named an unchanged XI from the game against Liverpool.
“I don’t think Ten Hag likes making lots of changes,” said Scholes.
“He likes players having rhythm, but with the schedule and the amount of games they’ve played, some of these players need a rest now.
“I thought Shaw looked like he needed a rest tonight, Casemiro looks like he needs a rest.
“They can give a few young players a taste of European football [next week] and hopefully that will stand them in good stead for the future.”